The upstream software is built so as to run from the build environment and look for data in ../Data. In Debian the binaries belong in /usr/bin and the data belongs in /usr/share. With this patch the binaries will run from any directory. A better fix would be to allow setting of the Data directory via an environment variable or a variable passed to MAKE at build time. This could be contributed back to upstream.
Some apps segfault when non-FASTA data is inputted, and this is flagged as a security concern. I suspect there are still ways to segfault this app, but at least this fixes an obvious crash. Also fixes https://code.google.com/p/ampliconnoise/issues/detail?id=10